Skip navigation
Skip navigation

Validation of the 6-Month GRACE score in predicting 1-year mortality of patients with acute coronary syndrome admitted to the Arabian Gulf hospitals

Thalib, Lukman; Furuya-Kanamori, Luis; AlHabib, Khalid F; Alfaleh, Hussam F; AlShamiri, Mostafa Q; Amin, Haitham; Al Suwaidi, Jassim; Sulaiman, Kadhim; Almahmeed, Wael; Alsheikh-Ali, Alawi A; Al-Motarreb, Ahmed; Doi, Suhail A R

Description

Acute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge is a widely used ACS prediction model for risk of mortality (low, intermediate, and high); however, it has not yet been validated in patients from the Arabian Gulf. This prospective multicenter study (second Gulf Registry of Acute Coronary Events) provides detailed...[Show more]

dc.contributor.authorThalib, Lukman
dc.contributor.authorFuruya-Kanamori, Luis
dc.contributor.authorAlHabib, Khalid F
dc.contributor.authorAlfaleh, Hussam F
dc.contributor.authorAlShamiri, Mostafa Q
dc.contributor.authorAmin, Haitham
dc.contributor.authorAl Suwaidi, Jassim
dc.contributor.authorSulaiman, Kadhim
dc.contributor.authorAlmahmeed, Wael
dc.contributor.authorAlsheikh-Ali, Alawi A
dc.contributor.authorAl-Motarreb, Ahmed
dc.contributor.authorDoi, Suhail A R
dc.date.accessioned2017-02-28T00:18:38Z
dc.date.available2017-02-28T00:18:38Z
dc.identifier.issn0003-3197
dc.identifier.urihttp://hdl.handle.net/1885/112713
dc.description.abstractAcute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge is a widely used ACS prediction model for risk of mortality (low, intermediate, and high); however, it has not yet been validated in patients from the Arabian Gulf. This prospective multicenter study (second Gulf Registry of Acute Coronary Events) provides detailed information of the GRACE risk score postdischarge in patients from the Arabian Gulf. Its prognostic utility was validated at 1-year follow-up in over 5000 patients with ACS from 65 hospitals in 6 Arabian Gulf countries (Bahrain, Saudi Arabia, Qatar, Oman, United Arab Emirates, and Yemen). Overall, the goodness of fit (Hosmer and Lemeshow statistic P value = .826), calibration, and discrimination (area under the receiver operating characteristic curve = 0.695; 95% confidence interval: 0.668-0.722) were good. The GRACE risk score postdischarge can be used to stratify 1 year mortality risk in the Arabian Gulf population; it does not require further calibration and has a good discriminatory ability.
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Gulf RACE-2 is a Gulf Heart Association (GHA) project and was financially supported by the GHA, Sanofi-Aventis, and the Deanship of Scientific Research at King Saud University, Riyadh, Saudi Arabia (Research group number: RG-1436-013). L.F.K. is funded by an Endeavour Postgraduate Scholarship (#3781_2014), an Australian National University Higher Degree Scholarship, and a Fondo para la Innovacio´n, Ciencia y Tecnologı´a Scholarship (#095-FINCyTBDE- 2014).
dc.format6 pages
dc.format.mimetypeapplication/pdf
dc.publisherSAGE Publications (UK and US)
dc.rights© The Author(s) 2016, SAGE
dc.sourceAngiology
dc.subjectgrace risk score
dc.subjectacute coronary syndrome
dc.subjectmortality
dc.subjectpostdischarge
dc.subjectvalidation
dc.titleValidation of the 6-Month GRACE score in predicting 1-year mortality of patients with acute coronary syndrome admitted to the Arabian Gulf hospitals
dc.typeJournal article
local.identifier.citationvolume68
dc.date.issued2017-03-01
local.publisher.urlhttps://au.sagepub.com/
local.type.statusPublished Version
local.contributor.affiliationDoi, Suhail A. R., Department of Health Services Research and Policy, CMBE Research School of Population Health, The Australian National University
local.contributor.affiliationFuruya-Kanamori, Luis, Department of Health Services Research and Policy, CMBE Research School of Population Health, The Australian National University
local.identifier.essn1940-1574
local.bibliographicCitation.issue3
local.bibliographicCitation.startpage251
local.bibliographicCitation.lastpage256
local.identifier.doi10.1177/0003319716659179
dcterms.accessRightsOpen Access
CollectionsANU Research Publications

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator