The implication of amino acid mutations at flavivirus NS1-2A cleavage site on NS1’ protein production
-
Altmetric Citations
Bettadapura, J.; Addis, S. N. K.
Description
Aims: The presence of a C-terminally extended form of NS1 (NS1’ protein) has been previously reported in encephalitic flaviviruses, due to the presence of -1 programmed ribosomal frameshift at the N-terminal of NS2A protein. This present study is aimed to further confirm that the NS1’ protein production is independent of the authentic cleavage at NS1-2A junction. Methodology and results: Six different constructs (P1-Leu, P2-Asp, P3-Phe, P3-Leu, P3-Gly and P5-8 Ala) containing various...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2015 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/112403 |
Source: | Malaysian Journal of Microbiology |
DOI: | 10.21161/mjm.71815 |
Access Rights: | Open Access |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Addis_The_Implication_of_Amino_Acid_2015.pdf | 476.38 kB | Adobe PDF | ![]() |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 19 May 2020/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator