Skip navigation
Skip navigation

Review: T follicular helper cells in transplantation

Walters, Giles Desmond; Vinuesa, Carola G.


The recently described T follicular helper (Tfh) cell is required for the production of high affinity antibody. After contact with follicular dendritic cells, Tfh cells move into the germinal centre and provide help to B cells both by direct B cell-T cell interaction and production of IL-21. This drives proliferation, differentiation, and affinity maturation of the B cells to produce plasma cells capable of secreting high-affinity antibody. Circulating Tfh cells are produced by movement of Tfh...[Show more]

CollectionsANU Research Publications
Date published: 2016-08
Type: Journal article
Source: Transplantation
DOI: 10.1097/TP.0000000000001217


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator