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Upper Versus Lower Gastrointestinal Delivery for Transplantation of Fecal Microbiota in Recurrent or Refractory Clostridium difficile Infection: A Collaborative Analysis of Individual Patient Data From 14 Studies

Furuya-Kanamori, Luis; Doi, Suhail A R; Paterson, David L; Helms, Stefan K; Yakob, Laith; McKenzie, Samantha J; Garborg, Kjetil; Emanuelsson, Frida; Stollman, Neil; Kronman, Matthew P; Clark, Justin; Huber, Charlotte A; Riley, Thomas V; Clements, Archie C A


GOALS The aim of this study was to compare upper gastrointestinal (UGI) versus lower gastrointestinal (LGI) delivery routes of fecal microbiota transplantation (FMT) for refractory or recurrent/relapsing Clostridium difficile infection (CDI). BACKGROUND FMT has been proven to be a safe and highly effective therapeutic option for CDI. Delivery, however, could be via the UGI or LGI routes, and it is unclear as to which route provides better clinical outcome. STUDY A systematic search for studies...[Show more]

CollectionsANU Research Publications
Date published: 2016-03-11
Type: Journal article
Source: Journal of clinical gastroenterology
DOI: 10.1097/MCG.0000000000000511
Access Rights: Open Access


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