Electrophysiological premotor processing in Huntington's disease: an issue of functional connectivity
Huntington’s disease is a neurodegenerative disease which presents with cognitive, motor and emotional-behavioural changes. Neural degeneration begins up to 20 years prior to symptom onset, arising initially in the striatum. Motor symptoms are a hallmark; disturbances occur due to disruption of crucial motor pathways through atrophy. However, these are not seen until much later in the disease. Such findings raise questions about the role internal processes...[Show more]
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