An analysis of the putative role of ROQUIN as a T cell RING-directed ubiquitin ligase
An analysis of the putative role of ROQUIN as a T cell RING-directed ubiquitin ligase Abstract: Acquiring long-term protective immunity involves the generation and recall production of high affinity antibodies by B cells in response to foreign antigen. This occurs only with the help of T cells. T follicular helper (Tfh) cells in particular are specialised in homing to B cell-enriched follicles and germinal centres (GCs) of secondary lymphoid organs where they provide selective paracrine signals...[Show more]
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