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Ectopic expression of RNA-dependent RNA polymerase in Drosophila melanogaster and microRNAs identification in Helicoverpa armigera

Duan, Guowen

Description

Drosophila melanogaster, along with all insects and the vertebrates, lacks an RNA-dependent RNA polymerase (RdRp) gene. We therefore asked whether the C. elegans RdRp genes could be introduced into Drosophila in order to study the effects on RNAi. This system also allowed us to ask whether there were any effects on development, possibly due to interference with microRNA (miRNA) regulation of genes. To address these questions, we introduced the two C. elegans RdRp genes, rrf-1 and ego-1, into D....[Show more]

CollectionsOpen Access Theses
Date published: 2011-06
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/109318

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