Skip navigation
Skip navigation

Safe and effective: anti-tumour necrosis factor therapy use in pregnant patients with Crohn disease and ulcerative colitis

Kiely, C J; Subramaniam, K; Platten, J; Pavli, P

Description

Biological therapy, particularly the anti-tumour necrosis factor (TNF) antibodies, infliximab and adalimumab, are used for the maintenance of remission for patients with inflammatory bowel diseases (IBD). We present 21 pregnancies in IBD patients exposed to anti-TNF agents between 2007 and 2014. Our study demonstrates that anti-TNF therapy is safe and effective in pregnancy. Rates of foetal complications are similar to IBD cohorts from the pre anti-TNF era.

dc.contributor.authorKiely, C J
dc.contributor.authorSubramaniam, K
dc.contributor.authorPlatten, J
dc.contributor.authorPavli, P
dc.date.accessioned2016-09-29T04:30:48Z
dc.date.available2016-09-29T04:30:48Z
dc.identifier.issn1444-0903
dc.identifier.urihttp://hdl.handle.net/1885/109111
dc.description.abstractBiological therapy, particularly the anti-tumour necrosis factor (TNF) antibodies, infliximab and adalimumab, are used for the maintenance of remission for patients with inflammatory bowel diseases (IBD). We present 21 pregnancies in IBD patients exposed to anti-TNF agents between 2007 and 2014. Our study demonstrates that anti-TNF therapy is safe and effective in pregnancy. Rates of foetal complications are similar to IBD cohorts from the pre anti-TNF era.
dc.publisherWiley
dc.rights© 2016 Royal Australasian College of Physicians
dc.sourceInternal medicine journal
dc.subjectcrohn disease
dc.subjectinflammatory bowel disease
dc.subjectpregnancy
dc.subjecttumour necrosis factor-alpha
dc.subjectulcerative colitis
dc.titleSafe and effective: anti-tumour necrosis factor therapy use in pregnant patients with Crohn disease and ulcerative colitis
dc.typeJournal article
local.identifier.citationvolume46
dc.date.issued2016-05-11
local.publisher.urlhttp://au.wiley.com/WileyCDA/
local.type.statusPublished Version
local.contributor.affiliationKiely, C. J., Medical School, The Australian National University
local.contributor.affiliationPavli, P., Medical School, The Australian National University
local.identifier.essn1445-5994
local.bibliographicCitation.issue5
local.bibliographicCitation.startpage616
local.bibliographicCitation.lastpage619
local.identifier.doi10.1111/imj.13057
CollectionsANU Research Publications

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator