Skip navigation
Skip navigation

DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations

Andrews, T Daniel; Jeelall, Yogesh; Talaulikar, Dipti; Goodnow, Christopher C; Field, Matthew A

Description

Background. Massively parallel sequencing technology is being used to sequence highly diverse populations of DNA such as that derived from heterogeneous cell mixtures containing both wild-type and disease-related states. At the core of such molecule tagging techniques is the tagging and identification of sequence reads derived from individual input DNA molecules, which must be first computationally disambiguated to generate read groups sharing common sequence tags, with each read group...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
URI: http://hdl.handle.net/1885/108871
Source: PeerJ
DOI: 10.7717/peerj.2074

Download

File Description SizeFormat Image
01_Andrews_DeepSNVMiner_2016.pdf1.66 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator