Model building to facilitate understanding of Holliday junction and heteroduplex formation, and Holliday junction resolution
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Selvarajah, Geeta; Selvarajah, Susila
Description
Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and computer-animated video, we included a model building activity using pipe cleaners. Biotechnology undergraduates (n = 108) used the model to simulate Holliday...[Show more]
Collections | ANU Research Publications |
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Date published: | 2016-07 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/108866 |
Source: | Biochemistry and molecular biology education |
DOI: | 10.1002/bmb.20964 |
Access Rights: | Open Access |
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