Model building to facilitate understanding of Holliday junction and heteroduplex formation, and Holliday junction resolution
Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and computer-animated video, we included a model building activity using pipe cleaners. Biotechnology undergraduates (n = 108) used the model to simulate Holliday...[Show more]
|Collections||ANU Research Publications|
|Source:||Biochemistry and molecular biology education|
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