Skip navigation
Skip navigation

Model building to facilitate understanding of Holliday junction and heteroduplex formation, and Holliday junction resolution

Selvarajah, Geeta; Selvarajah, Susila


Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and computer-animated video, we included a model building activity using pipe cleaners. Biotechnology undergraduates (n = 108) used the model to simulate Holliday...[Show more]

CollectionsANU Research Publications
Date published: 2016-07
Type: Journal article
Source: Biochemistry and molecular biology education
DOI: 10.1002/bmb.20964
Access Rights: Open Access


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator