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Phase transitions in hydrophobe/phospholipid mixtures: hints at connections between pheromones and anaesthetic activity

Borsacchi, Silvia; Geppi, Marco; Macchi, Sara; Ninham, Barry W.; Fratini, Emiliano; Ambrosi, Moira; Baglioni, Piero; Lo Nostro, Pierandrea


The phase behavior of a mixture of a typical insect pheromone (olean) and a phospholipid (DOPC)/water dispersion is extensively explored through SAXS, NMR and DSC experiments. The results mimic those obtained with anaesthetics in phospholipid/water systems. They also mimic the behavior and microstructure of ternary mixtures of a membrane mimetic, bilayer-forming double chained surfactants, oils and water. Taken together with recent models for conduction of the nervous impulse, all hint at lipid...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
Source: Physical Chemistry Chemical Physics
DOI: 10.1039/C6CP00659K


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