Striatal morphology correlates with frontostriatal electrophysiological motor processing in Huntington's disease: an IMAGE-HD study
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Turner, Lauren M.; Jakabek, David; Wilkes, Fiona A.; Croft, Rodney J.; Churchyard, Andrew; Walterfang, Mark; Velakoulis, Dennis; Looi, Jeffrey C. L.; Apthorp, Apthorp; Georgiou-Karistianis, Nellie
Description
BACKGROUND: Huntington’s disease (HD) causes progressive atrophy to the striatum, a critical node in frontostriatal circuitry. Maintenance of motor function is dependent on functional connectivity of these premotor, motor, and dorsolateral frontostriatal circuits, and structural integrity of the striatum itself. We aimed to investigate whether size and shape of the striatum as a measure of frontostriatal circuit structural integrity was correlated with functional...[Show more]
Collections | ANU Research Publications |
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Date published: | 2016 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/108620 |
Source: | Brain and Behavior |
DOI: | 10.1002/brb3.511 |
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