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Changing topological patterns in normal aging using large-scale structural networks.

Zhu, Wanlin; Wen, Wei; He, Yong; Xia, Aihua; Sachdev, Perminder Singh; Anstey, Kaarin


We examine normal aging from the perspective of topological patterns of structural brain networks constructed from two healthy age cohorts 20 years apart. Based on graph theory, we constructed structural brain networks using 90 cortical and subcortical regions as a set of nodes and the interregional correlations of grey matter volumes across individual brains as edges between nodes, and further analyzed the topological properties of the age-specific networks. We found that the brain structural...[Show more]

CollectionsANU Research Publications
Date published: 2010-08-17
Type: Journal article
Source: Neurobiology of Aging 33.5 (2012): 899-913
DOI: 10.1016/j.neurobiolaging.2010.06.022


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