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Hematopoiesis leading to a diversity of dendritic antigen-presenting cell types

Petvises, Sawang; O'Neill, Helen

Description

Hematopoietic stem cells (HSCs) undergo expansion and differentiation, giving rise to all terminally differentiated blood cells throughout life. HSCs are found in distinct anatomical sites during development, and in adults, hematopoiesis occurs predominantly on the luminal side of the bone cavity in bone marrow. Millions of newly formed blood cells are generated per second to accommodate the short half-life of hematopoietic cells. For this to happen, HSCs must sustain their self-renewal...[Show more]

CollectionsANU Research Publications
Date published: 2011-07-12
Type: Journal article
URI: http://hdl.handle.net/1885/10536
Source: Immunology and Cell Biology 90.4 (2012): 372-378
DOI: 10.1038/icb.2011.47

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