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Murine spleen contains a diversity of myeloid and dendritic cells distinct in antigen presenting function

Hey, Ying Y; O'Neill, Helen


The spleen contains multiple subsets of myeloid and dendritic cells (DC). DC are important antigen presenting cells (APC) which induce and control the adaptive immune response. They are cells specialized for antigen capture, processing and presentation to naıve T cells. However, DC are a heterogeneous population and each subset differs subtly in phenotype, function and location. Similarly, myeloid cell subsets can be distinguished which can also play an important role in the regulation of...[Show more]

CollectionsANU Research Publications
Date published: 2012-10-29
Type: Journal article
Source: Journal of Cellular and Molecular Medicine 16.11 (2012): 2611-2619
DOI: 10.1111/j.1582-4934.2012.01608.x


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