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Myelopoiesis in spleen-producing distinct dendritic-like cells

Tan, Jonathan K. H.; Neill, Helen C.


Dendritic cells (DC) represent a heterogeneous class of antigen presenting cells (APC). Previously we reported a distinct myeloid dendritic-like cell present in spleen, as an 'in vivo' counterpart to cells produced in murine spleen long-term cultures (LTC-DC). These cells, named 'L-DC', were found to be functionally and phenotypically distinct from conventional (c)DC, plasmacytoid (p)DC and monocytes. These results suggested that spleen may represent a niche for development of L-DC from...[Show more]

CollectionsANU Research Publications
Date published: 2012-07-29
Type: Journal article
Source: Journal of Cellular and Molecular Medicine 16.8 (2012): 1924-33
DOI: 10.1111/j.1582-4934.2011.01490.x


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