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The Effects of Age-Related Modifications on the Stability and Function of Human Eye Lens Crystallins

Ray, Nicholas John


The crystallins are the primary proteins of the eye lens and are largely responsible for its high transparency, high refractive index and long-term stability. While the crystallin proteins are often able to remain stable for the lifetime of an individual, the lack of protein turnover in the lens means they are subject to a wide range of age-related, post-translational modifications. These modifications build up over the protein’s life and many are correlated...[Show more]

CollectionsOpen Access Theses
Date published: 2015-08
Type: Thesis (PhD)


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