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APOE Genotype and Cognitive Functioning in a Large Age-Stratified Population Sample.

Jorm, Anthony F; Mather, Karen; Butterworth, Peter; Christensen, Helen; Easteal, Simon; Anstey, Kaarin


There is evidence that the cognitive effects of Alzheimer's disease can be seen decades before disease diagnosis. If this is the case, then the apolipoprotein E (APOE) *E4 allele might be expected to have effects on cognitive functioning earlier in the life span. To assess such effects, the authors examined data on the *E4 allele and cognitive functioning from a population sample of 6,560 Caucasians covering the age groups of 20-24, 40-44, and 60-64 years. Participants were assessed on tests of...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Neuropsychology
DOI: 10.1037/0894-4105.21.1.1


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