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Tailoring minimalist self-assembling peptides for localized viral vector gene delivery

Rodriguez, Alexandra; Wang, Ting-Yi; Bruggeman, Kiara; Li, Rui; Williams, Richard J; Parish, Clare L.; Nisbet, David


Viral vector gene delivery is a promising technique for the therapeutic administration of proteins to damaged tissue for the improvement of regeneration outcomes in various disease settings including brain and spinal cord injury, as well as autoimmune diseases. Though promising results have been demonstrated, limitations of viral vectors, including spread of the virus to distant sites, neutralization by the host immune system, and low transduction efficiencies have stimulated the investigation...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Nano Research
DOI: 10.1007/s12274-015-0946-0


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