Transcriptomic analysis of mouse EL4 T cells upon T cell activation and in response to protein synthesis inhibition via cycloheximide treatment
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Lim, Pek Siew; Hardy, Kristine; Peng, Kaimen; Shannon, Frances
Description
T cell activation involves the recognition of a foreign antigen complexed to the major histocompatibility complex on the antigen presenting T cell to the T cell receptor. This leads to activation of signaling pathways, which ultimately leads to induction of key cytokine genes responsible for eradication of foreign antigens. We used the mouse EL4 T cell as a model system to study genes that are induced as a result of T cell activation using phorbol myristate acetate (PMA) and calcium ionomycin...[Show more]
Collections | ANU Research Publications |
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Date published: | 2016 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/103523 |
Source: | Genomics Data |
DOI: | 10.1016/j.gdata.2015.12.009 |
Access Rights: | Open Access |
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01_Lim_Transcriptomic_analysis_of_2016.pdf | 1.21 MB | Adobe PDF |
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