Ayers, Brandon; Luders, Eileen; Cherbuin, Nicolas; Joshi, Shantanu. H
We present a shape-based approach for calculating the thickness of the corpus callosum. The corpus callosum is delineated from the MRI midsagittal white matter boundary and represented as a parameterized curve consisting of the top and bottom boundaries by a trained expert. The top and bottom boundaries are first represented in a quotient space of open curves, and then elastically matched under a geometric framework that generates an optimal correspondence between their 'shapes'. This matching...[Show more]
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