Skip navigation
Skip navigation

GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations

Ryan, Joanne; Artero, Sylvaine; Carrière, Isabelle; Maller, Jerome; Meslin, Chantal; Ritchie, Karen; Ancelin, Marie-Laure

Description

A number of genome-wide association studies (GWAS) have investigated risk factors for major depressive disorder (MDD), however there has been little attempt to replicate these findings in population-based studies of depressive symptoms. Variants within three genes, BICC1, PCLO and GRM7 were selected for replication in our study based on the following criteria: they were identified in a prior MDD GWAS study; a subsequent study found evidence that they influenced depression risk; and there is a...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
URI: http://hdl.handle.net/1885/103276
Source: European Neuropsychopharmacology
DOI: 10.1016/j.euroneuro.2015.08.022

Download

File Description SizeFormat Image
01_Ryan_GWAS-identified_risk_variants_2016.pdf425.52 kBAdobe PDF    Request a copy
02_Ryan_GWAS-identified_risk_variants_2016.pdf64.74 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator