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Biological functions of Mycobacterium tuberculosis-specific CD4 +T cells were impaired by tuberculosis pleural fluid

Li, Qin; Li, Li; Fu, Xiaoying; Wang, Hui; Lao, Suihua; Yang, Binyang; Wu, Changyou


The local milieu at the site of Mycobacterium tuberculosis infection that modulates T-cell functions is the main battleground for the host to build counter-M. tuberculosis immune responses. CD4+T cells are enriched predominantly in tuberculosis pleurisy and their roles are of considerable importance, but their nature and functional profiles linked with local condition remain elusive. Here we evaluated the functions of M. tuberculosis-specific CD4+T cells from the major three profiles: cytokines...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Immunology Letters
DOI: 10.1016/j.imlet.2011.03.008


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