Li, Rui; Horgan, Conor; Long, Benjamin; Rodriguez, Alexandra; Mather, Lauren; Barrow, Colin J; Nisbet, David; Williams, Richard J
Hydrogels formed by the self-assembly of peptides are promising biomaterials. The bioactive and biocompatible molecule Fmoc-FRGDF has been shown to be an efficient hydrogelator via a π-β self-assembly mechanism. Herein, we show that the mechanical properties and morphology of Fmoc-FRGDF hydrogels can be effectively and easily manipulated by tuning both the final ionic strength and the rate of pH change. The increase of ionic strength, and consequent increase in rate of gelation and stiffness,...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.