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Age-related cortical thinning in cognitively healthy individuals in their 60s: The PATH Through Life study

Shaw, Marnie; Sachdev, Perminder Singh; Cherbuin, Nicolas; Anstey, Kaarin


Although it is recognized that the human cortex thins with age, longitudinal estimates of thinning patterns specific to healthy young-old age (<75 years) individuals are lacking. Importantly, many neurodegenerative disorders first manifest between midlife and old age, and normative estimates may provide a reference for differential change associated with such disorders. Here, we provide longitudinal estimates of cortical thinning observed over 12 years in a large group (n = 396) of healthy...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
Source: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2015.12.009


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