Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
-
Altmetric Citations
Ritchie, Matthew E.; Liu, Ruijie; Carvalho, Benilton S; Bahlo, Melanie; Foote, Simon; Brown, Matthew A; Cox, Mathew B; McMorran, Brendan; Jensen, Cathy J; Stewart, Graeme; Broadley, Simon; Irizarry, Rafael A.
Description
Background: Illumina's Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw allele A and allele B intensities from each SNP into genotype calls (AA, AB, BB). Various algorithms which make use of different statistical models are available for this task. We compare four methods (GenCall, Illuminus, GenoSNP and CRLMM) on data where the true genotypes are known in advance and data from a recently...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2011 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/102819 |
Source: | BMC Bioinformatics |
DOI: | 10.1186/1471-2105-12-68 |
Access Rights: | Open Access |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Ritchie_Comparing_genotyping_2011.pdf | 655.81 kB | Adobe PDF |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 19 May 2020/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator