Can evolutionary rate matrices be estimated from allele frequencies?
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Description
This paper is a work in progress in which aims to combine the principles of population genetics and continuous-time Markovian evolutionary models to estimate evolutionary rate matrices from the current observed state of a single genome. A model is proposed in which sections of the genome which are not susceptible to natural selection are considered to be a statistical ensemble of individual genomic sites. Each site is a representative from a stationary distribution of allele frequencies 0 < 8 <...[Show more]
Collections | ANU Research Publications |
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Date published: | 2015 |
Type: | Conference paper |
URI: | http://hdl.handle.net/1885/102755 |
Source: | BIOINFORMATICS 2015 - 6th International Conference on Bioinformatics Models, Methods and Algorithms, Proceedings; Part of 8th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2015 |
DOI: | 10.5220/0005253701830188 |
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01_Burden_Can_evolutionary_rate_matrices_2015.pdf | 410.69 kB | Adobe PDF | Request a copy |
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