High-sensitivity C-reactive protein (hs-CRP) as a biomarker for trastuzumab-induced cardiotoxicity in HER2-positive early-stage breast cancer: a pilot study
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Onitilo, Adedayo A.; Engel, Jessica M.; Stankowski, Rachel V.; Liang, Hong; Berg, Richard; Doi, Suhail
Description
Monitoring of left ventricular ejection fraction (LVEF) is the current standard for detection of trastuzumab-induced cardiotoxicity; however, time-to-diagnosis and cost of assessment are suboptimal in women with early-stage breast cancer. We assessed the utility of B-type natriuretic peptide (BNP), high-sensitivity C-reactive protein (hs-CRP), and cardiac troponin I (cTnI) as serum biomarkers for early detection of trastuzumab-induced cardiotoxicity. Fifty-four women with human epidermal growth...[Show more]
Collections | ANU Research Publications |
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Date published: | 2012 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/102719 |
Source: | Breast Cancer Research and Treatment |
DOI: | 10.1007/s10549-012-2039-z |
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01_Onitilo_High-sensitivity_C-reactive_2012.pdf | 261.11 kB | Adobe PDF | Request a copy |
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