Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers
Prostate cancer (PCa) is the most commonly diagnosed malignancy among men living in Western countries and a major cause of cancer-related deaths. Biopsy-based diagnosis of PCa is usually performed following an elevated serum prostate-specific antigen (PSA) measurement and/or abnormal digital rectal examination (DRE). The deficiencies of serum PSA as a biomarker have been well documented (Roobol & Carlsson 2013). While it is highly specific for tissues of prostatic origin, PSA is not cancer...[Show more]
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