Variation in incidence of pediatric Crohn's disease in relation to latitude and ambient ultraviolet radiation: A systematic review and analysis
Background: Pediatric Crohn's disease (CD) is a lifelong, debilitating, and costly disease. In previous studies, CD incidence increased with higher geographic latitude in the Northern Hemisphere. This may indicate a role for lower vitamin D status as a risk factor for CD. Analysis of worldwide incidence of pediatric CD has not been previously reported. Methods: We undertook a systematic review of population-based studies reporting incidence of pediatric CD and published between 2003 and 2013....[Show more]
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|Source:||Inflammatory Bowel Diseases|
|01_Holmes_Variation_in_incidence_of_2015.pdf||381.52 kB||Adobe PDF||Request a copy|
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