Mapping Domains for ZIC3 Molecular Function
The zinc finger of the cerebellum (Zic) genes encode a family of transcriptional regulators critical for early embryogenesis. All ZIC proteins contain a zinc finger domain (ZFD) and other evolutionary conserved regions. They are pleiotropic in nature since they can influence gene expression directly by acting as transcription factors due to their ability to bind target DNA sequences, or indirectly as co-factors by interacting with protein partners. Little is...[Show more]
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