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Interleukin-6 (-174C) polymorphism and the risk of sepsis in very low birth weight infants: meta-analysis

Chauhan, M; McGuire, W


BACKGROUND The guanidine to cytosine transition at position -174 nucleotides relative to the transcription start site in the interleukin (IL)-6 gene has been implicated as a genetic risk factor for the development of sepsis in very low birth weight (VLBW) infants. However, association studies have reported conflicting findings and have generally been underpowered to exclude modest effect sizes. AIM To systematically assess the evidence for the association of the IL-6 (-174C) polymorphism with...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition
DOI: 10.1136/adc.2007.134205


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