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Cytokine gene polymorphisms in preterm infants with necrotising enterocolitis: genetic association study

Henderson, G.; Craig, S.; Baier, R. J.; Helps, N.; Brocklehurst, P.; McGuire, W.


BACKGROUND The inflammatory cytokine cascade is implicated in the pathogenesis of necrotising enterocolitis (NEC). Genetic association studies of cytokine polymorphisms may help to detect molecular mechanisms that are causally related to the disease process. AIM To examine associations between the common genetic variants in candidate inflammatory cytokine genes and NEC in preterm infants. METHODS Multi-centre case-control and genetic association study. DNA samples were collected from 50 preterm...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition
DOI: 10.1136/adc.2007.119933
Access Rights: Open Access


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