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In vivo and in vitro metabolism of the designer anabolic steroid furazadrol in thoroughbred racehorses

Waller, Christopher C; Cawley, Adam T; Suann, Craig J; Ma, Paul; McLeod, Malcolm D

Description

Furazadrol ([1',2']isoxazolo[4',5':2,3]-5α-androstan-17β-ol) is a designer anabolic androgenic steroid that is readily available via the internet. It contains an isoxazole fused to the steroid A-ring which offers metabolic stability and noteworthy anabolic activity raising concerns over the potential for abuse of this compound in equine sports. The metabolism of furazadrol was studied by in vivo and in vitro methods for the first time. Urinary furazadrol 17-sulfate and furazadrol 17-glucuronide...[Show more]

CollectionsANU Research Publications
Date published: 2016-05-30
Type: Journal article
URI: http://hdl.handle.net/1885/100911
Source: Journal of pharmaceutical and biomedical analysis
DOI: 10.1016/j.jpba.2016.02.031

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