Predictive value of lung function below the normal range and respiratory symptoms for progression of chronic obstructive pulmonary disease
BACKGROUND Chronic obstructive pulmonary disease (COPD) is an insidiously starting disease. Early detection has high priority because of the possibility of early implementation of smoking cessation interventions. An evidence based model for case finding of COPD is not yet available. OBJECTIVE To describe the early development of COPD, and to assess the predictive value of early signs (respiratory symptoms, lung function below the normal range, reversibility). DESIGN AND METHODS In a prospective...[Show more]
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