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Dynamics of A Three-Variable Nonlinear Model of Vasomotion: Comparison of Theory and Experiment

Parthimos, D.; Haddock, Rebecca; Hill, C.E.; Griffith, T.M.

Description

The effects of pharmacological interventions that modulate Ca(2+) homeodynamics and membrane potential in rat isolated cerebral vessels during vasomotion (i.e., rhythmic fluctuations in arterial diameter) were simulated by a third-order system of nonlinear differential equations. Independent control variables employed in the model were [Ca(2+)] in the cytosol, [Ca(2+)] in intracellular stores, and smooth muscle membrane potential. Interactions between ryanodine- and inositol...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/100882
Source: Biophysical Journal
DOI: 10.1529/biophysj.107.106278

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