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Muller cell expression of glutamate cycle related proteins and anti-apoptotic proteins in early human retinal development

Georges, P; Cornish, E E; Provis, J M; Madigan, M C


AIMS The distribution of glutamate cycle related proteins (glutamine synthetase (GS) and GLAST) and anti-apoptotic proteins (Bcl-2 and Bcl-X) was investigated in Müller cells during early human retinal development, relative to the onset of expression of synaptophysin, a presynaptic vesicle protein. METHODS Using frozen sections of human fetal eyes (13-22 weeks gestation) (n = 10), Bcl-2, Bcl-X, GS, GLAST, and synaptophysin immunoreactivities (IR) were imaged using fluorescence microscopy and...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: British Journal of Ophthalmology
DOI: 10.1136/bjo.2005.078014


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