Skip navigation
Skip navigation

Evaluation of a chiral cubane-based Schiff base ligand in asymmetric catalysis reactions

Biegasiewicz, Kyle F; Ingalsbe, Michelle L; St. Denis, Jeffrey D; Gleason, James L; Ho, Junming; Coote, Michelle; Savage, G Paul; Priefer, Ronny


Recently, a novel chiral cubane-based Schiff base ligand was reported to yield modest enantioselectivity in the Henry reaction. To further explore the utility of this ligand in other asymmetric organic transformations, we evaluated its stereoselectivity in cyclopropanation and Michael addition reactions. Although there was no increase in stereocontrol, upon computational evaluation using both M06L and B3LYP calculations, it was revealed that a pseudo six-membered ring exists, through H-bonding...[Show more]

CollectionsANU Research Publications
Date published: 2012-10-22
Type: Journal article
Source: Beilstein Journal of Organic Chemistry
DOI: 10.3762/bjoc.8.207
Access Rights: Open Access


File Description SizeFormat Image
01_Biegasiewicz_Evaluation_of_a_chiral_2012.pdfPublished Version789.85 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator