Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation
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Elms, Paul; Scurry, Andrew; Davies, Jennifer; Willoughby, Catherine; Hacker, Terry; Bogani, Debora; Arkell, Ruth
Description
The Zic genes are the vertebrate homologues of the Drosophila Odd-paired gene. Mutations in two of these genes are associated with human congenital genetic disorders. Mutation of human and mouse Zic2 is associated with holoprosencephaly which is caused by a defect of ventral forebrain development and mutation of human and mouse Zic3 is associated with a X-linked heterotaxy syndrome that results from a failure of left-right axis formation. The embryological role of the Zic genes in these...[Show more]
Collections | ANU Research Publications |
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Date published: | 2004-09 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/100212 |
Source: | Gene Expression Patterns |
DOI: | 10.1016/j.modgep.2004.03.003 |
Access Rights: | Open Access |
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File | Description | Size | Format | Image |
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01_Elms_Overlapping_and_Distinct_2004.pdf | 647.9 kB | Adobe PDF |
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