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Interaction of short-term depression and firing dynamics in shaping single neuron encoding

Mohan, Ashutosh; McDonnell, Mark D.; Stricker, Christian


We investigated how the two properties short-term synaptic depression of afferent input and postsynaptic firing dynamics combine to determine the operating mode of a neuron. While several computational roles have been ascribed to either, their interaction has not been studied. We considered two types of short-term synaptic dynamics (release-dependent and release-independent depression) and two classes of firing dynamics (regular firing and firing with spike-frequency adaptation). The...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Frontiers in Computational Neuroscience
DOI: 10.3389/fncom.2013.00041


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