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In vivo hippocampal measurement and memory: a comparison of manual tracing and automated segmentation in a large community sample

Cherbuin, Nicolas; Meslin, Chantal; Sachdev, Perminder Singh; Anstey, Kaarin


While manual tracing is the method of choice in measuring hippocampal volume, its time intensive nature and proneness to human error make automated methods attractive, especially when applied to large samples. Few studies have systematically compared the performance of the two techniques. In this study, we measured hippocampal volumes in a large (N = 403) population-based sample of individuals aged 44–48 years using manual tracing by a trained researcher and automated procedure using Freesurfer...[Show more]

CollectionsANU Research Publications
Date published: 2009-04-16
Type: Journal article
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0005265


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