Skip navigation
Skip navigation

A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader

Loscha, Karin; Jaudzems, Kristaps; Ioannou, Charikleia; Su, Xun-Cheng; Hill, Flynn R; Otting, Gottfried; Dixon, Nicholas; Liepinsh, Edvards


The helicase loader protein DnaI (the Bacillus subtilis homologue of Escherichia coli DnaC) is required to load the hexameric helicase DnaC (the B. subtilis homologue of E. coli DnaB) onto DNA at the start of replication. While the C-terminal domain of DnaI belongs to the structurally well-characterized AAA+ family of ATPases, the structure of the N-terminal domain, DnaI-N, has no homology to a known structure. Three-dimensional structure determination by nuclear magnetic resonance (NMR)...[Show more]

CollectionsANU Research Publications
Date published: 2009-03-02
Type: Journal article
Source: Nucleic Acids Research
DOI: 10.1093/nar/gkp092


File Description SizeFormat Image
Loscha_Novel2009.pdf8.57 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator