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A family of RS domain proteins with novel subcellular localization and trafficking

Kavanagh, Steven J; Schulz, Thomas C; Davey, Philippa; Claudianos, Charles; Russell, Carrie; Rathjen, Peter D


We report the sequence, conservation and cell biology of a novel protein, Psc1, which is expressed and regulated within the embryonic pluripotent cell population of the mouse. The Psc1 sequence includes an RS domain and an RNA recognition motif (RRM), and a sequential arrangement of protein motifs that has not been demonstrated for other RS domain proteins. This arrangement was conserved in a second mouse protein (BAC34721). The identification of Psc1 and BAC34721 homologues in vertebrates and...[Show more]

CollectionsANU Research Publications
Date published: 2005-03-01
Type: Journal article
Source: Nucleic Acids Research
DOI: 10.1093/nar/gki269


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