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Identification and characterization of polymorphisms at the HSA alpha1-acid glycoprotein (ORM*) gene locus in Caucasians

Owczarek, Catherine; Owczarek, A L; Board, Philip


Human a1-acid glycoprotein (AGP) or orosomucoid (ORM) is a major acute phase protein that is thought to play a crucial role in maintaining homeostasis. Human AGP is the product of a cluster of at least two adjacent genes located on HSA chromosome 9. Using a range of restriction endonucleases we have investigated DNA variation at the locus encoding the AGP genes in a panel of healthy Caucasians. Polymorphisms were identified using BamHI, EcoRI, BglII, PvuII, HindIII, TaqI and MspI. Non-random...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: Genetics and Molecular Biology
DOI: 10.1590/S1415-47572002000100004


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