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Evolutionary history of LINE-1 in the major clades of placental mammals

Waters, Paul; Dobigny, Gauthier; Waddell, Peter J; Robinson, Terence J


BACKGROUND: LINE-1 constitutes an important component of mammalian genomes. It has a dynamic evolutionary history characterized by the rise, fall and replacement of subfamilies. Most data concerning LINE-1 biology and evolution are derived from the human and mouse genomes and are often assumed to hold for all placentals. METHODOLOGY: To examine LINE-1 relationships, sequences from the 3′ region of the reverse transcriptase from 21 species (representing 13 orders across Afrotheria,...[Show more]

CollectionsANU Research Publications
Date published: 2007-01-17
Type: Journal article
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0000158


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