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The status of dosage compensation in the multiple X chromosomes of the platypus

Deakin, Janine; Hore, Tim; Koina, Edda; Graves, Jennifer


Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XX females and XY males in therian mammals (marsupials and “placentals”) by inactivating one X chromosome in female somatic cells. However, compensation seems not to be strictly required to equalize the expression of most Z-borne genes between ZZ male and ZW female birds. Whether dosage compensation...[Show more]

CollectionsANU Research Publications
Date published: 2008-07-25
Type: Journal article
Source: PLoS Genetics
DOI: 10.1371/journal.pgen.1000140


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