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The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it

Stevceva, L; Pavli, Paul; Husband, Alan J; Doe, W


BACKGROUND: Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been described. Therefore in this study we characterized the cells involved in the acute phase of the colitis and compared those findings to what is known about human IBD. METHODS: Colitis was induced in BALB/C and C57Bl6 mice by ingestion of 2.5% and 5% DSS in the drinking water for 8 days. Cells were labelled by...[Show more]

CollectionsANU Research Publications
Date published: 2001-09-10
Type: Journal article
Source: BMC Clinical Pathology
DOI: 10.1186/1472-6890-1-3


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