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Vestige: maximum likelihood phylogenetic footprinting

Wakefield, Matthew; Maxwell, Peter; Huttley, Gavin Austin


BACKGROUND: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from multiple species and identifying the DNA regions that have diverged less than neutral DNA. Vestige is a phylogenetic footprinting package built on the PyEvolve toolkit that uses probabilistic molecular evolutionary modelling to represent aspects of sequence evolution, including the conventional divergence measure...[Show more]

CollectionsANU Research Publications
Date published: 2005-05-29
Type: Journal article
Source: BMC Bioinformatics
DOI: 10.1186/1471-2105-6-130


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