Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals
Download (1.21 MB)
-
Altmetric Citations
Patel, Vidushi; Deakin, Janine; Graves, Jennifer; Cooper, Steven; Fulton, Bob; Graves, Tina; Warren, Wesley; Wilson, Richard K
Description
BACKGROUND: Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the α- and β-globin clusters expanded, and then were separated onto different chromosomes. The previous finding of a fossil β-globin gene (ω) in the marsupial α-cluster, however, suggested that duplication of the α-β cluster onto two chromosomes, followed by lineage-specific gene loss and duplication,...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2008-07-25 |
Type: | Journal article |
URI: | http://hdl.handle.net/10440/109 http://digitalcollections.anu.edu.au/handle/10440/109 |
Source: | BMC Biology |
DOI: | 10.1186/1741-7007-6-34 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
Patel_Platypus2008.pdf | 1.21 MB | Adobe PDF |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator