MHC-linked and un-linked class 1 genes in the wallaby
Download (1.4 MB)
Siddle, Hannah V; Deakin, Janine; Coggill, P; Hart, Elizabeth; Cheng, Yuanyuan; Wong, Emily; Harrow, Jennifer; Beck, Stephan; Belov, Katherine
BACKGROUND: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions. However, there is a fundamental difference between the organization of class I genes in mammals and non-mammals. Non-mammals have a single classical gene responsible for antigen presentation, which is linked to the antigen processing genes, including TAP. This organization allows co-evolution...[Show more]
|Collections||ANU Research Publications|
|Siddle_MHC-linked2009.pdf||1.4 MB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator